Table 2 Disease Activity Index (DAI) to assess clinical colitis in mice (modified based on Aharoni et al., 2006; Wirtz et al., 2007)
From: Dietary phenethylisothiocyanate attenuates bowel inflammation in mice
Score | Body wt change (%) | Internal intestinal bleeding, FOBT test strip (colorimetric) | Rear end visible bleeding+ inflammation | Stool consistency | *Rectal prolapse |
|---|---|---|---|---|---|
0 | Gain, loss <1 | No color change | Negative | Normal | None |
1 | Loss 1-5 | - | Either one, mild | - | - |
2 | Loss 5-10 | Color change | Either one, severe | Loose | Observed |
3 | Loss 10-15 | - | Both, mild | - | Â |
4 | Loss >15 | - | Both, severe | Diarrhea | - |