Di-, tri- and tetra-5'-O-phosphorothioadenosyl substituted polyols as inhibitors of Fhit: Importance of the α-β bridging oxygen and β phosphorus replacement

Table 3 Physicochemical characteristics of compounds 2–17.

Comp.	³¹P NMR in D₂O	MS-MALDI	Yield
No	H₃PO₄ chemical shifts [ppm]	(M-1) m/z	%]
2	58.95; 57.64	752	24
3	58.82; 57.69	840	53
4	57.14; 56.92	812	50
5 ^*	58.46; 58.24; 30.28	815	54
6a ^*	2.3	750	35
6b ^*	56.83	782	42
6c	115.86; 115.159	814	25
7b	57.64; 57.33	780	21
8b	59.13; 58.94	781	10
9b	57.32; 58.15	766	34
10b	60.65; 60.31	764	55
11b	71.85; 71.17	798	40
12 ^*	56.94; 46.82	1267	20
13 ^*	56.28	1516	35
14 ^*	57.12; 46.71	1018	21
15 ^*	57.56	1127	60
16b	60.17; 59.13; 58.49; 57.41	1125	15
17 ^*	56.61; 45.95	877	37