BMC Chemical Biology

Table 1 Cytotoxicity of compounds 1 and 2 against U937 leukemia cells in vitro^a

From: Synthesis and preliminary cytotoxicity study of a cephalosporin-CC-1065 analogue prodrug

Compd.	IC₅₀ (nM)^b
1	0.09
2	0.9

^aCells were incubated with drugs for 48 h and the experiments were performed according to our previously published method;²⁷^bIC₅₀ values are defined as the minimal drug concentration necessary to inhibit incorporation of [³H]thymidine by 50%, and are the averages of three experiments.

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