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Table 4 Fold changes in gene expression in cells treated with LPS (1 μg/ml) as compared to endogenous expression levels in untreated cells.

From: MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages

Gene symbol Accession No. Gene name Fold change in response to LPS
C3 NM_009778 Complement component 3 3.02
Il15 NM_008357 Interleukin 15 6.39
Ltb NM_008518 Lymphotoxin B 4.48
Atf1 NM_007497 Activating transcription factor 1 4.43
Bcl10 NM_009740 B-cell leukemia/lymphoma 10 22.13
Cflar NM_009805 CASP8 and FADD-like apoptosis regulator 14.01
Edg2 NM_010336 Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 6.49
Relb NM_009046 Avian reticuloendotheliosis viral (v-rel) oncogene related B 21.38
Stat1 NM_009283 Signal transducer and activator of transcription 1 5.89
Cd40 NM_011611 Cluster of Differentiation 40 112.83
Nr2c2 NM_011630 Nuclear receptor subfamily 2, group C, member 2 -4.07
Peli1 NM_030015 Pellino 1 5.48
  1. Triptolide (55.5 nM) did not have any effect on these genes.