Table 1 In vivo experimental set-up for acute and chronic colitis models
From: Dietary phenethylisothiocyanate attenuates bowel inflammation in mice
Groups | Acute model (5 days induction, ad libitum) | Chronic model (36 days induction,, ad libitum) | Treatment (14 days, once daily) | Comment |
|---|---|---|---|---|
Water | Tap water | Tap water | Vehicle (9% DMSO+corn oil) | Healthy control |
DSS | 3% DSS | 2.5% DSS (3 days) followed by tap water (6 days), 4 cycles | Vehicle (9% DMSO+corn oil) | Diseased control* |
PEO | 3% DSS | 2.5% DSS (3 days) followed by tap water (6 days), 4 cycles | PEO 75 mg/kg (>95% PEITC) | Unknown test group |
5-ASA | 3% DSS | 2.5% DSS (3 days) followed by tap water (6 days), 4 cycles | 5-ASA 50 mg/kg | Reference test group |