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Table 3 Scoring system for inflammation-associated histological changes in the colon (Wirtz et al., 2007)

From: Dietary phenethylisothiocyanate attenuates bowel inflammation in mice

Score Histologic changes
0 No evidence of inflammation
1 Low level of inflammation with scattered infiltrating mononuclear cells (1--2 foci)
2 Moderate inflammation with multiple foci
3 High level of inflammation with increased vascular density and marked wall thickening
4 Maximal severity of inflammation with transmural leukocyte infiltration and loss of goblet cells