Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility

BMC Chemical Biology

Table 3 Kinase profiling report for CID755673

48 kinases were interrogated using a single-dose in vitro kinase assay at 10 μM CID755673. -20 to +20% inhibition, baseline levels; >20 to 49% inhibition, compound only marginally actively inhibits the kinase; >50% inhibition, compound is actively inhibiting the kinase. The assay was performed by Caliper Life Sciences (Hanover, MD).