Table 2 Representative proteins selected from each cluster and negative candidates for experimental verification
Cluster No. | Representative Protein |
|---|---|
1 | ITPR1 (inositol 1,4,5-triphosphate receptor, type 1) |
2 | DAPK1 (death-associated protein kinase 1) |
3 | PIK3CG (phosphoinositide-3-kinase, catalytic, gamma polypeptide), PIK3C2B (phosphoinositide-3-kinase, class 2, beta polypeptide) |
4 | PARP14 (poly (ADP-ribose) polymerase family, member 14) |
5 | PIP5K3 (phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III) |
6 | PLCB1 (phospholipase C, beta 1) |
7 | CHD4 (chromodomain helicase DNA binding protein 4) |
8 | KIF1A (kinesin family member 1A), KIF21B (kinesin family member 21B) |
9 | ACACA (acetyl-Coenzyme A carboxylase alpha) |
10 | GTF2IRD2 (GTF2I repeat domain containing 2) |
11 | RGPD5 (RANBP2-like and GRIP domain-containing protein 5) |
Negative | Proteins predicted not to bind to incednine |
1 | BECN1 (Beclin-1) |
2 | PARP1 (poly (ADP-ribose) polymerase family, member 1) |
3 | KIF5B (kinesin family member 5B) |