Figure 4

Compound 4g completely inhibited the invasion of MDA-MB-231 cells. Cells were seeded in Matrigel^TM-coated Boyden chambers and were incubated for 24 h with DMEM (untreated) or a medium containing 1 μM of compound 4g (1 μM) or 10 μM compound 4g (10 μM); the photographs shows the cell on the lower surface of the filter (invaded) stained with the Diff-Quick solution. The % inhibition of the invasion of MDA-MB-231 by compound 4g was presented. The data represent the mean value ± S.D. for three independent experiments. ^* P < 0.05 versus control, Student's t-test.