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Table 3 Inhibition of the proliferation of tumor and endothelial cells by compound 4g

From: Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives

Compound

Anti-proliferative activity (IC50inμ M)

LM8G7

OVSAHO

UV♀2

4g

15± 0.6*

24± 3.6**

62± 1.9

Cisplatin

30 ± 24

15 ± 0.6

12 ± 0.4

Suramin

12 ± 2.8

14 ± 24

34 ± 1.4

  1. *p 0.05 versus control, **p 0.01 versus control, Mann-Whitney U test.