BMC Chemical Biology

Table 1 Cytotoxicity of compounds 5, 6, and doxorubicin against U937 leukemia cells in vitro^a

From: Synthesis and cytotoxicity of a biotinylated CC-1065 analogue

Compd.	IC₅₀ (nM)^b
5	0.09
6	0.7
Doxorubicin	100

^aCells were incubated with drugs for 48 h and the experiments were performed according to our previously published method [26]; ^bIC₅₀ values are defined as the minimal drug concentration necessary to inhibit incorporation of [³H]thymidine by 50%, and are the averages of three experiments.

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