Figure 4From: Chemical cleavage reactions of DNA on solid support: application in mutation detectionDetection of C.C mismatch of 547 bp DNA fragment by using hydroxylamine / piperidine assay. The control trace (homoduplex, top) shows no cleavage peak and the mismatched DNA trace (heteroduplex, bottom) displays two strong cleavage peaks of 5'FAM sequence and 3'HEX sequence at the mismatched C bases.Back to article page