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Figure 3 | BMC Chemical Biology

Figure 3

From: Studies on the synthesis, characterization, binding with DNA and activities of two cis-planaramineplatinum(II) complexes of the form: cis-PtL(NH3)Cl2 where L = 3-hydroxypyridine and 2,3-diaminopyridine

Figure 3

(A): Interaction of pBR322 plasmid DNA with increasing concentrations of cisplatin (lanes 0–4: 1: 1 μM; 2: 2.5 μM; 3: 5 μM; 4: 10 μM.) and transplatin (lanes 7–13: 7: 0 8: 1 μM; 9: 2.5 μM; 10: 5 μM; 11: 10 μM, 13: 0.) ranging from 1 to 10 μM. (B): Interaction between pBR322 plasmid DNA and increasing concentrations of AH3 and AH7 ranging from 5 μM to 50 μM: (Lanes 0 to 10: lane 0: untreated plasmid, 1:5 μM; 2: 10 μM; 3: 15 μM; 4: 20 μM; 5: 25 μM; 6: 30 μM; 7: 35 μM; 8: 40 μM; 9: 45 μM; 10: 50 μM).

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BMC Chemical Biology

ISSN: 1472-6769