From: Studies on the synthesis, characterization, binding with DNA and activities of two cis-planaramineplatinum(II) complexes of the form: cis-PtL(NH3)Cl2 where L = 3-hydroxypyridine and 2,3-diaminopyridine
A2780
A2780-cisR
IC50A2780cisR/IC50A2780
A2780ZD0473R
IC50
RF
AH3
3.8 ± 1.0
6.9 ± 1.0
1.8
7.5 ± 1.0
AH7
11.7 ± 1.4
8.5 ± 1.3
0.7
10.6 ± 1.0
Cisplatin
1.1 ± 0.4
2.3 ± 0.4
2.1
2.2 ± 0.4