Figure 3From: Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virusInhibition of HCV RNA replication by 25-hydroxycholesterol in a dose-dependent manner. Activity data from Huh-7 cells transiently transfected with luc/NS3-3'/5.1 replicon RNA and treated with 25-HC or 100 U/ml IFNγ for 24 h. Bars represent the mean ± standard deviation of triplicate samples. An asterisk above a bar indicates a significant decrease in replication compared to untreated cells (p < 0.01).Back to article page