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Figure 3 | BMC Chemical Biology

Figure 3

From: Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus

Figure 3

Inhibition of HCV RNA replication by 25-hydroxycholesterol in a dose-dependent manner. Activity data from Huh-7 cells transiently transfected with luc/NS3-3'/5.1 replicon RNA and treated with 25-HC or 100 U/ml IFNγ for 24 h. Bars represent the mean ± standard deviation of triplicate samples. An asterisk above a bar indicates a significant decrease in replication compared to untreated cells (p < 0.01).

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