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Figure 1 | BMC Chemical Biology

Figure 1

From: Chemical tools selectively target components of the PKA system

Figure 1

Chemical structures of cyclic nucleotides. (A) Model of the bovine RIα subunit (PDB-ID 1RGS) with bound agonist (Sp-8-AHA-cAMPS, left) and antagonist (Rp-8-AHA-cAMPS, right). The figure was created using standard settings in VMD 1.8.4 [58]. Chemical structures of Sp-cAMPS (B) and Rp-cAMPS (C) analogs. Arrows indicate positions of attached linkers.

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