Table 4 Clusters of metabolic drug scopes in the human irreversible network.
From: Local and global modes of drug action in biochemical networks
Cluster Id | Number of drugs in cluster | Average scope size | Significant compounds in consensus scope |
|---|---|---|---|
I | 62 | 8 | - |
II | 24 | 10 | - |
III | 85 | 230 | ATP, Pyruvate, Galactose |
IV | 35 | 40 | Arachidonate |
V | 14 | 11 | - |
VI | 15 | 21 | - |
VII | 13 | 27 | - |
VIII | 5 | 110 | Pyruvate |
IX | 8 | 21 | - |
X | 1 | 12 | CoA |
XI | 1 | 25 | CoA |
XII | 2 | 53 | Tryptophan |
XIII | 3 | 21 | - |
XIV | 2 | 14 | - |
XV | 1 | 16 | - |
XVI | 2 | 11 | - |
XVII | 1 | 24 | - |
XVIII | 1 | 30 | Tyrosine |
XIX | 1 | 16 | - |