Figure 1

Tumoral soluble factors derived from breast cancer cell line ZR75.30 increase adhesion. The cell adhesion assay shows the endothelial activation, which is proportional to the adhesion of human myeloma U937 cells to HUVECs. Each bar represents the average of three independent experiments performed in triplicates. Statistical significance when compared to the control group is defined as: p < 0.05 (*) and p < 0.01 (**). The error bars indicate ± standard error of the mean.