Table 3 Clusters of metabolic drug scopes in the human reversible network.
From: Local and global modes of drug action in biochemical networks
Cluster Id | Number of drugs in cluster | Average scope size | Significant compounds in consensus scope |
|---|---|---|---|
I | 77 | 9 | - |
II | 94 | 339 | ATP, Pyruvate, Tyrosine, Galactose |
III | 35 | 40 | Arachidonate |
IV | 30 | 130 | Pyruvate |
V | 12 | 244 | Pyruvate, Tyrosine, Galactose |
VI | 8 | 21 | - |
VII | 1 | 44 | Tryptophan, Tyrosine |
VIII | 4 | 11 | - |
IX | 5 | 21 | - |
X | 3 | 22 | - |
XI | 2 | 14 | - |
XII | 2 | 11 | - |
XIII | 1 | 30 | - |
XIV | 1 | 33 | Tyrosine |
XV | 1 | 16 | - |